PrimeSTAR Max DNA Polymerase is a unique high-performance DNA polymerase for PCR. PrimeSTAR Max DNA Polymerase has the highest fidelity and fastest extension speed of any commercially available enzyme, along with extremely high sensitivity, processivity, and specificity. It includes an elongation factor to provide efficient priming and extension, greatly reducing the time required for annealing and extension steps. As a result, PrimeSTAR Max DNA Polymerase can be used for exceptionally fast high-speed PCR. Since it is formulated as a premix that supports hot-start PCR, it's also excellent for high-throughput experiments. When you need fast reaction times and/or highly accurate amplification for cloning and expression, structural studies, or evolutionary analyses, PrimeSTAR Max DNA Polymerase is the enzyme of choice.
PrimeSTAR Max DNA Polymerase is suitable for reactions occurring in the presence of excess nucleic acid. Such extraneous DNA in a reaction mix ordinarily inhibits PCR amplification when using conventional polymerases because the amount of effective polymerase available is limited by nonspecific binding. The superior processivity of PrimeSTAR Max DNA Polymerase prevents such inhibition by excess nucleic acid, resulting in a much higher success rate for PCR with minimal optimization of conditions required. Furthermore, the antibody-mediated hot start formulation prevents false initiation events during the reaction assembly due to mispriming and primer digestion. Since PrimeSTAR Max DNA Polymerase is configured as a 2-fold premix containing reaction buffer and dNTP mixture, it allows rapid preparation of reactions and is useful for high-throughput applications.
