Capable of outstanding performance for both routine high-fidelity PCR and challenging templates or reaction conditions, PrimeSTAR GXL DNA Polymerase is the most robust high-fidelity PCR enzyme commercially available. It provides high yield, high specificity, and high accuracy for not only standard reactions, but also excels in PCR with GC-rich templates, in the presence of eXcess template, and for amplification of Long products up to 30 kb (GXL). Simplify your PCR and save time by relying on one enzyme system works regardless of conditions, with minimal optimization required.
PrimeSTAR GXL DNA Polymerase includes a modified PrimeSTAR HS enzyme and an additional elongation factor which in combination provide unsurpassed processivity. PrimeSTAR GXL DNA Polymerase has outstanding performance in reactions containing excess nucleic acid. Such extraneous DNA in a reaction mix ordinarily inhibits PCR amplification by conventional polymerases because the amount of effective polymerase available is limited by nonspecific binding. The superior processivity of PrimeSTAR GXL DNA Polymerase prevents such inhibition by excess nucleic acid, resulting in a much higher success rate for PCR with minimal optimization of conditions required. Furthermore, the antibody-mediated hot start formulation prevents false initiation events during the reaction assembly due to mispriming and primer digestion.
