Cyclophilin C-associated protein (CyCAP) has been proposed as the endogenous equivalent of the immunosuppressant drug, cyclosporin A. It competes with cyclosporin A for binding to cyclophilin C. It is also known as lectin, galactoside-binding, soluble, 3 binding protein (Lgals3bp); Cyp-C-associated protein, 90K, Ppicap, and MAC-2BP. CyCAP expression has been reported in brain, kidney, macrophage cells, dermal fibroblasts, and keratinocytes. Roles for CyCAP have been reported in wound healing and macrophage activation via association with nuclear factor of activated T-cells (NFAT).
This product is an affinity-purified IgG antibody that recognizes rat CyCAP. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, immunocytochemical (ICC) detection, or immunoprecipitation (IP) of rat CyCAP.
