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Products >  IBL >  Metabolic_Diseases >  Antibodies >  Angiotensinogen_Mouse_Rat

Anti-Mouse/Rat Angiotensinogen (405) Rabbit IgG Antibody

Angiotensinogen (also known as serpin peptidase inhibitor, clade A, member 8; Serpin A8, Ang, Ang II, PAT, and ANRT) is a protein implicated in controlling blood pressure. It is an essential component of the renin-angiotensin system (RAS). In response to lowered blood pressure, the enzyme renin cleaves angiotensinogen to produce angiotensin-I. Angiotensin-I is further cleaved by angiotensin-converting enzyme (ACE) to yield the physiologically active peptide angiotensin-II. Angiotensin II is also implicated in regulation of insulin-like growth factor 1 (IGF-1) expression. Urinary excretion of angiotensinogen in a rat model of hypertension was shown to be a marker of intrarenal RAS activity.

This product is an affinity-purified IgG antibody that recognizes mouse/rat angiotensinogen protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of mouse/rat angiotensinogen protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 28101A, 28101B
  • Target Name: Mouse/rat angiotensinogen protein
  • Antigen: Mouse angiotensinogen C-terminal synthetic peptide
  • Application: WB, IHC
  • Specificity: Reacts with mouse and rat angiotensinogen
  • Target Entrez Gene ID: 11606, 24179

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1 µg/mL
  • Immunohistochemical techniques: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Serpin peptidase inhibitor, clade A, member 8; Serpin A8, Ang, AngII, PAT, ANRT




 
 
Products
New Cat. # Product Package Size Price # of Units Select
28101A Anti-Mouse/Rat Angiotensinogen (405) Rabbit IgG Affinity Purify 10 ug $100.00
28101B Anti-Mouse/Rat Angiotensinogen (405) Rabbit IgG Affinity Purify 100 ug $499.00
 

 



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