Anti-Human GLUT-5 Rabbit IgG Antibody

Metabolism in mammalian cells requires a constant supply of glucose. Since glucose is a hydrophilic molecule, it must be transported across the cell membrane by dedicated proteins, known as glucose transporters. In humans, these proteins are encoded by the facilitative glucose transporter (GLUT) gene family, now known as the solute carrier family 2 or SLC2A gene family. GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine. It facilitates the transport of fructose from the intestinal lumen into enterocytes. In addition, GLUT5 is expressed in adipose tissue, skeletal muscle, brain, testis, and kidney. GLUT5 is also known as solute carrier family 2 (facilitated glucose/fructose transporter), member 5 (SLC2A5); and glucose transporter type 5, small intestine. This GLUT5 antibody detects microglia selectively in immnostaining, and does not react with monocytes or monocyte-derived macrophages.