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Products >  Cell_Biology >  mTOR_Signaling >  Antibodies >  mLST8_Human

Anti-Human mLST8 (L17) Rabbit IgG Antibody

Human mTOR-associated protein, LST8 homolog (mLST8) is a subunit of two protein complexes that associate with mammalian target of rapamycin (mTOR), known as mTORC1 and mTORC2. Both complexes regulate cell growth and survival in response to nutrient and hormonal signals. Within mTORC1, mLST8 interacts directly with and enhances the kinase activity of mTOR. In nutrient-poor conditions, mLST8 stabilizes the interaction between mTOR and regulatory-associated protein of mTOR (RAPTOR). The MLST8 gene is conserved over a wide range of species, from yeast to human. mLST8 is also known as Gable (GBL), GbetaL, mammalian lethal with SEC13 protein 8, TORC subunit LST8, target of rapamycin complex subunit LST8, G protein beta subunit-like, POP3, and WAT1.

This product is an affinity-purified IgG antibody that recognizes human mLST8 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human mLST8 protein.

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Features

  • Cat.#: 28013A, 28013B
  • Target Name: Human mLST8 protein
  • Antigen: Human mLST8 N-terminal synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 64223

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.5–5.0 µg/mL
  • Immunoprecipitation: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Gable, GBL, GbetaL, mammalian lethal with SEC13 protein 8, TORC subunit LST8, target of rapamycin complex subunit LST8, G protein beta subunit-like, POP3, WAT1




 
 
Products
Cat. # Product Contents Size Price Units Select
28013A Anti-Human mLST8 (L17) Rabbit IgG Affinity Purify 10 ug $113.00 *
28013B Anti-Human mLST8 (L17) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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