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Products >  Cell_Biology >  mTOR_Signaling >  Antibodies >  Rictor_Human

Anti-Human Rictor (R1291) Rabbit IgG Antibody

Rapamycin-insensitive companion of mTOR (Rictor) is encoded by the RICTOR gene in humans. Rictor shares homology with pianissimo from D. discoidieum, STE20p from S. pombe, and AVO3p from S. cerevisiae. It is involved in the control of the mammalian target of rapamycin (mTOR) and is a subunit of mTORC2. mTORC2 is activated by growth factors but, unlike mTORC1, the complex is insensitive to nutrient levels. Rictor interacts with mTOR kinase to modulate the phosphorylation of protein Kinase C alpha (PKC alpha) and the actin cytoskeleton. Rictor is also known as RPTOR independent companion of MTOR, complex 2; PIA, KIAA1999, AVO3 homolog, hAVO3, AVO3, MGC39830, and TORC2-specific protein AVO3.

This product is an affinity-purified IgG antibody that recognizes human Rictor protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human Rictor protein.

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Features

  • Cat.#: 28039A, 28039B
  • Target Name: Human Rictor protein
  • Antigen: Human Rictor synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 253260

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–3 µg/mL
  • Immunoprecipitation: 1–3 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

RPTOR independent companion of MTOR, complex 2; PIA, KIAA1999, AVO3 homolog, hAVO3, AVO3, MGC39830, TORC2-specific protein AVO3




 
 
Products
Cat. # Product Contents Size Price Units Select
28039A Anti-Human Rictor (R1291) Rabbit IgG Affinity Purify 10 ug $113.00 *
28039B Anti-Human Rictor (R1291) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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