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Products >  Cell_Biology >  mTOR_Signaling >  Antibodies >  Rheb_Human

Anti-Human Rheb (R165) Rabbit IgG Antibody

Ras homolog enriched in brain (Rheb) is a member of the small GTPase superfamily of proteins and is encoded by the RHEB gene in humans. Rheb is a lipid-anchored, cell-membrane protein that contains five repeats of the RAS-related GTP-binding region. It alternates between GDP- and GTP-bound forms; post-translational modification by addition of a farnesyl group is required for this activity. Rheb is an essential component of the insulin/TOR/S6K signaling pathway that regulates cell cycle progression and cell growth. Rheb activates mammalian target of rapamycin (mTOR) kinase within the mTORC1 complex. Rheb is also known as GTP-binding protein Rheb and RHEB2.

This product is an affinity-purified IgG antibody that recognizes human Rheb protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human Rheb protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 28015A, 28015B
  • Target Name: Human Rheb protein
  • Antigen: Human Rheb C-terminal synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 6009

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.5–5.0 µg/mL
  • Immunoprecipitation: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

GTP-binding protein Rheb, RHEB2




 
 
Products
Cat. # Product Package Size Price # of Units Select
28015A Anti-Human Rheb (R165) Rabbit IgG Affinity Purify 10 ug $100.00
28015B Anti-Human Rheb (R165) Rabbit IgG Affinity Purify 100 ug $499.00
 

 



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