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Products >  Cell_Biology >  mTOR_Signaling >  Antibodies >  Raptor_Human

Anti-Human Raptor Rabbit IgG Antibody

Regulatory associated protein of mTOR, complex 1 (Raptor) is encoded by the RPTOR gene. It is involved in the control of the mammalian target of rapamycin (mTOR) and is a subunit of mTORC1. Raptor binds to mTOR kinase and functions as a scaffold for recruiting mTORC1 substrates. It also associates with eukaryotic translation initiation factor 4E-binding protein 1 (EIF4BP1) and ribosomal protein S6 kinase (S6K1). Raptor negatively regulates mTOR kinase but positively regulates S6K1. Raptor also interacts with unc-51-like kinase 1 (ULK1) in a nutrient-dependent manner. Raptor is also known as p150 target of rapamycin (TOR)-scaffold protein, KIAA1303, KOG1, and Mip1.

These products are affinity-purified IgG antibodies that recognize human Raptor protein. The antibodies were raised in rabbit using synthetic peptides and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human Raptor protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 28011A, 28011B
  • Target Name: Human Raptor protein
  • Antigen: Human Raptor (middle portion) synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 57521

  • Cat.#: 28037A, 28037B
  • Target Name: Human Raptor protein
  • Antigen: Human Raptor N-terminal synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 57521

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.5–5.0 µg/mL (Cat.# 28011); 1–3 µg/mL (Cat.# 28037)
  • Immunoprecipitation: 1–5 µg/mL (Cat.# 28011); 0.25–3.0 µg/mL (Cat.# 28037)

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

RPTOR, p150 target of rapamycin (TOR)-scaffold protein, KIAA1303, KOG1, Mip1




 
 
Products
Cat. # Product Package Size Price # of Units Select
28011A Anti-Human Raptor (R984) Rabbit IgG Affinity Purify 10 ug $100.00
28011B Anti-Human Raptor (R984) Rabbit IgG Affinity Purify 100 ug $499.00
28037A Anti-Human Raptor (R1) Rabbit IgG Affinity Purify 10 ug $100.00
28037B Anti-Human Raptor (R1) Rabbit IgG Affinity Purify 100 ug $499.00
 

 



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