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Products >  Cell_Biology >  Signal_Transduction >  Antibodies >  Platelet-Human_Monoclonal

Human Platelet Monoclonal Antibody

GMP-140, which is also known as P-selectin or CD62P, is a cell adhesion molecule that is important for platelet recruitment and aggregation at sites of hemorrhage or inflammation. In unstimulated platelets, GMP-140 is localized internally. Upon platelet activation (such as via thrombin), GMP-140 moves to the platelet cell surface where it participates in the adhesion of neutrophils to injured endothelium. The binding of platelets has been shown to be inhibited by anti-platelet antibody such as GMP-140 antibody (also known as CD62P antibody). 

Takara's human platelet monoclonal antibody was raised against activated human platelet GMP-140.

  At-A-Glance   Documents   Images & Data   Resources

Specificity

  • These products react with human GMP-140 (P-selectin).
  • These products do not react with reduced antigen.
  • These products do not affect platelet aggregation and platelet adhesion.
  • Each clone recognizes a different epitope on the GMP-140 molecule.

Applications

  • GMP-140/CD62P detection on activated platelets
  • Western blot analysis under non-reducing and non-heating conditions
  • Immunohistochemistry of frozen tissue sections
  • Flow cytometry
  • Immunoprecipitation

Source

(for all Clones)

CloneCat.#Immun.Immun. hostSubclassAntibody titer
WGA-1M062human plateletBALB/c mouseIgG11: 4,000
PL7-6M063human plateletBALB/c mouseIgG11: 4,000

Storage

Lyophilized antibodies are stable at 4C for up to 2 years. The reconstituted antibodies can be stored at 4C for up to 6 months or at -20C for up to 1 year.

Notes

For research use only. Not for clinical diagnostics.

Form

Lyophilized (all antibodies) 

Reconstitution

Dissolve in 50 µL of distilled water (final conc.: 2.0 mg/mL, containing 0.1% sodium azide)

References




 
 
Products
Offers Cat. # Product Contents Size Price Units Select
M063 Monoclonal Anti-Human Platelet GMP-140 (P-selectin/CD62) (Clone PL7-6) 0.1 mg $427.00
M062 Monoclonal Anti-Human Platelet GMP-140 (P-selectin/CD62) (Clone WGA-1) 0.1 mg $427.00
 

 

 
 

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