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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_T-Z >  XIAP_Human

Anti-Human XIAP Rabbit IgG Antibody

Human X-linked inhibitor of apoptosis (XIAP) protein belongs to a family of apoptotic suppressor proteins that share a conserved motif, the baculovirus IAP repeat (BIR). The BIR motif is necessary for antiapoptotic function. XIAP plays a variety of other functional roles, such as also modulation of inflammatory signaling and immunity, mitogenic kinase signaling, cell proliferation, and copper homeostasis. XIAP acts as a caspase inhibitor by binding to the active site of caspase 3 and 7; it also inactivates caspase 9 by preventing it from forming active homodimers. Mutations in the XIAP gene are associated with X-linked lymphoproliferative syndrome. XIAP is also known as baculoviral IAP repeat-containing 4 (BIRC4), inhibitor of apoptosis protein 3 (IAP3), hIAP3, IAP-like protein, API3, ILP1, MIHA, and XLP2.

This product is an affinity-purified IgG antibody that recognizes human XIAP protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection of human XIAP protein.

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Features

  • Cat.#: 28059A, 28059B
  • Target Name: Human XIAP protein
  • Antigen: Human XIAP synthetic peptide
  • Specificity: Cross-reacts with mouse XIAP
  • Application: WB
  • Target Entrez Gene ID: 331

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.1–0.5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 50 µg/mL).

Alternative names

X-linked inhibitor of apoptosis, baculoviral IAP repeat-containing 4, BIRC4, inhibitor of apoptosis protein 3, IAP3, hIAP3, IAP-like protein, API3, ILP1, MIHA, XLP2




 
 
Products
Cat. # Product Contents Size Price Units Select
28059A Anti-Human XIAP Rabbit IgG Affinity Purify 5 ug $113.00 *
28059B Anti-Human XIAP Rabbit IgG Affinity Purify 50 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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