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Cell Biology

Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_T-Z >  Tti1_KIAA0408_Human

Anti-Human Tti1/KIAA0406 Rabbit IgG Antibody

TELO2 interacting protein 1 is a human homolog of the S. pombe Tel2 interacting protein 1, and is encoded by the TTI1 gene. It is part of the TTT complex that is required to stabilize the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. This complex regulates the response to DNA damage caused by radiation or DNA cross-linking agents. TTI1 also promotes the assembly, stabilizes, and maintains the activity of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2; these complexes are responsible for regulating cell growth and survival in response to nutrient and hormonal signals. TTI1 is also known as Tel2 interacting protein 1 homolog (S. pombe); Tel2 interacting protein 1 homolog, KIAA0406, and smg-10 homolog, nonsense mediated mRNA decay factor (SMG10).

This product is an affinity-purified IgG antibody that recognizes human TTI1 protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection of human TTI1 protein.

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  • Cat.#: 28117A, 28117B
  • Target Name: Human TTI1 protein
  • Antigen: Human TTI1 C-terminal synthetic peptide
  • Application: WB
  • Target Entrez Gene ID: 9675


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

TELO2 interacting protein 1; Tel2 interacting protein 1 homolog (S. pombe); Tel2 interacting protein 1 homolog, KIAA0406; smg-10 homolog, nonsense mediated mRNA decay factor; SMG10

Offers Cat. # Product Contents Size Price Units Select
28117A Anti-Human Tti1/KIAA0406 Rabbit IgG Affinity Purify 10 ug $113.00 *
28117B Anti-Human Tti1/KIAA0406 Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.



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