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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_O-S >  SCF_Human

Anti-Human SCF Rabbit IgG Antibody

Stem cell factor (SCF), encoded by the KITLG gene in humans, is a cytokine ligand that binds to the receptor tyrosine kinase c-Kit. SCF plays important roles in a variety of cellular functions, including hematopoiesis, spermatogenesis, melanogenesis, stem cell maintenance, mast cell development, and cell migration. Binding of SCF to the c-Kit receptor activates several signaling pathways mediated by phosphatidylinositol 3-kinase (PI3K), RAS/ERK, JAK/STAT, and MAP kinases. SCF is also known as KIT ligand, c-Kit ligand, KITL, KL-1, mast cell growth factor (MGF), SF, familial progressive hyperpigmentation 2 (FPH2), SHEP7, and steel factor.

These products are affinity-purified IgG antibodies that recognize human SCF protein. The antibodies were raised in rabbit using synthetic peptides and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human SCF protein.

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Features

  • Cat.#: 18111A, 18111B
  • Target Name: Human SCF protein
  • Antigen: Human SCF synthetic peptide
  • Specificity: Does not cross-react with mouse and rat SCF
  • Application: WB, IHC
  • Target Entrez Gene ID: 4254

  • Cat.#: 18114A
  • Target Name: Human SCF protein
  • Antigen: Human SCF synthetic peptide
  • Specificity: Cross-reacts with mouse and rat SCF
  • Application: WB
  • Target Entrez Gene ID: 4254

  • Cat.#: 18115A, 18115B
  • Target Name: Human SCF protein
  • Antigen: Human SCF synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 4254

  • Cat.#: 18116A, 18116B
  • Target Name: Human SCF protein
  • Antigen: Human SCF synthetic peptide
  • Specificity: Cross-reacts with mouse SCF
  • Application: WB, IHC
  • Target Entrez Gene ID: 4254

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL (Cat.# 18111, 18114, 18116); 2–5 µg/mL (Cat.# 18115)
  • Immunohistochemical techniques: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

KIT ligand, c-Kit ligand, KITLG, KITL, KL-1, mast cell growth factor, MGF, SF, familial progressive hyperpigmentation 2, FPH2, SHEP7, steel factor




 
 
Products
Offers Cat. # Product Contents Size Price Units Select
18111A Anti-Human SCF (K089) Rabbit IgG Affinity Purify 10 ug $113.00 *
  18111B Anti-Human SCF (K089) Rabbit IgG Affinity Purify 100 ug $499.00
  18114A Anti-Human SCF (K151) Rabbit IgG Affinity Purify 100 ug $499.00
  18115A Anti-Human SCF (K165) Rabbit IgG Affinity Purify 10 ug $113.00 *
  18115B Anti-Human SCF (K165) Rabbit IgG Affinity Purify 100 ug $499.00
  18116A Anti-Human SCF (K236) Rabbit IgG Affinity Purify 10 ug $113.00 *
  18116B Anti-Human SCF (K236) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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