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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_O-S >  RON_Human

Anti-Human RON (G1385) Rabbit IgG Antibody

Macrophage stimulating 1 receptor (c-met-related tyrosine kinase), encoded by the MST1R gene, is a cell-surface receptor that binds macrophage-stimulating protein (MSP). It was previously known as RON. The precursor protein is cleaved to generate the mature form, a heterodimer of disulfide-linked alpha and beta subunits. The beta subunit of MST1R/RON is phosphorylated at tyrosine residues upon activation by MSP. MST1R/RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation, and survival at the wound site. MST1R/RON is also known as CDw136, protein-tyrosine kinase 8 (PTK8), c-met-related tyrosine kinase, macrophage-stimulating protein receptor, MSP receptor, p185-Ron, CD136, MST1R variant RON30, MST1R variant RON62, and RON variant E2E3.

This product is an affinity-purified IgG antibody that recognizes human MST1R/RON protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human MST1R/RON protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18531A, 18531B
  • Target Name: Human MST1R/RON protein
  • Antigen: Human MST1R/RON C-terminal synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 4486

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 2–10 µg/mL
  • Immunoprecipitation: 2–10 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Macrophage stimulating 1 receptor (c-met-related tyrosine kinase); MST1R, RON, CDw136, protein-tyrosine kinase 8, PTK8, c-met-related tyrosine kinase, macrophage-stimulating protein receptor, MSP receptor, p185-Ron, CD136, MST1R variant RON30, MST1R variant RON62, RON variant E2E3




 
 
Products
Cat. # Product Package Size Price # of Units Select
18531B Anti-Human RON (G1385) Rabbit IgG Affinity Purify 100 ug $499.00
18531A Anti-Human RON (G1385) Rabbit IgG Affinity Purify 10 ug $113.00 *
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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