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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_O-S >  RIG-1_Human

Anti-Human RIG-I Antibody

Retinoic acid-inducible gene I protein (RIG-I) is double-stranded (ds) RNA helicase that is encoded by the DDX58 gene in humans. RIG-I is a member of the DEAD box protein family, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). In addition to the RNA helicase domain, RIG-I contains a caspase recruitment domain. RIG-I binds to 5'-triphosphorylated single-stranded (ss) RNA and short dsRNA (<1 kb). It is involved in recognition of viral dsRNA and regulation of the immune response to viral infection. RIG-I has also been suggested to play roles in granulocyte production and differentiation, bacterial phagocytosis, and regulation of cell migration. 

This product is an affinity-purified IgG antibody that recognizes human RIG-I protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) or immunocytochemistry detection of human RIG-I protein.

At-A-Glance Documents Images & Data

Features

  • Target Name: Human RIG-I protein
  • Antigen: Human RIG-I CTD domain synthetic peptide
  • Specificity: Cross-reacts with mouse RIG-I
  • Application: WB, ICC
  • Target Entrez Gene ID: 23586

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1 µg/mL
  • Immunocytochemistry: 1 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

DDX58, retinoic acid-inducible gene I protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, DEAD box protein 58, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, probable ATP-dependent RNA helicase DDX58, RIG1, RIG-I-like receptor 1 (RLR-1), DKFZp434J1111, FLJ13599




 
 
Products
Cat. # Product Package Size Price # of Units Select
28137A Anti-Human RIG-I (CTD) Rabbit IgG Affinity Purify 5 ug $114.00 *
28137B Anti-Human RIG-I (CTD) Rabbit IgG Affinity Purify 50 ug $525.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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