Takara
login | register | order now | view cart | feedback
Products
Cell Biology


Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_H-N >  hnRNP_B1_Human

Anti-Human hnRNP B1 Rabbit IgG Antibody

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein in the nucleus that are involved in gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA). After RNA splicing, hnRNPs remain bound to spliced introns and target them for subsequent degradation. hnRNPs also play a role in transporting mature mRNAs out of the nucleus. Over 30 hnRNPs are known in humans. hnRNP B1, also called hnRNP A2/B1, is encoded by the HNRPA2B1 gene, and belongs to the A/B subfamily of ubiquitously expressed hnRNPs. Alternative splicing results in two transcript variants that encode different isoforms. hnRNP A2/B1 has been shown to interact with casein kinase 2-alpha-1. Studies in mice suggest that hnRNP A2/B1 may regulate several tumor suppressors and oncogenes in glioblastomas. hnRNP B1 is also known as hnRNP A2/B1, hnRNP A2B1, hnRNP A2, RNPA2, HNRPA2, HNRPB1, SNRPB1, HNRNPA2, HNRNPB1, and HNRPA2B1.

This product is an affinity-purified IgG antibody that recognizes human hnRNP A2/B1 protein. The antibody was raised in rabbit using a synthetic petide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human hnRNP A2/B1 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18941A, 18941B
  • Target Name: Human hnRNP A2/B1
  • Antigen: Human hnRNP A2/B1 N-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 3181

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.5 µg/mL
  • Immunoprecipitation: 0.5–1.0 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

hnRNP A2/B1, hnRNP A2B1, hnRNP A2, RNPA2, HNRPA2, HNRPB1, SNRPB1, HNRNPA2, HNRNPB1, HNRPA2B1




 
 
Products
Cat. # Product Package Size Price # of Units Select
18941A Anti-Human hnRNP B1 Rabbit IgG Affinity Purify 10 ug $100.00
18941B Anti-Human hnRNP B1 Rabbit IgG Affinity Purify 100 ug $499.00
 

 



Clontech is a Takara Bio Company © 2014 Privacy Policy | Terms & Conditions