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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_E-G >  GFAT1

Anti-GFAT1 Rabbit IgG Antibody

Glutamine--fructose-6-phosphate transaminase 1 (GFAT1) catalyzes the formation of glucosamine 6-phosphate. It is the first and rate-limiting enzyme of the hexosamine pathway, in which fructose-6-phosphate is converted to N-acetylglucosamine-6-phosphate. The end-products of the hexosamine pathway are UDP-N-acetylglucosamine (UDP-GlcNAc) and other nucleotide hexosamines. Activation of the hexosamine pathway leads to insulin resistance, largely from deterioration of pancreatic beta-cell function through the induction of oxidative stress. GFAT1 is also known as glutamine:fructose 6 phosphate amidotransferase 1, hexosephosphate aminotransferase 1, D-fructose-6-phosphate amidotransferase 1, GFA, GFAT, GFPT, MSLG, CMSTA1, GFAT1m, and GFPT1L.

These products are affinity-purified IgG antibodies that recognize GFAT1 protein. The antibodies were raised in rabbit using synthetic peptides, and can be used for Western blot (WB) detection or immunoprecipitation (IP) of GFAT1 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 28121A, 28121B
  • Target Name: Human GFAT1 protein
  • Antigen: Human GFAT1 C-terminal synthetic peptide
  • Specificity: Cross-reacts with mouse and rat GFAT1
  • Application: WB, IP
  • Target Entrez Gene ID: 2673

  • Cat.#: 28123A, 28123B
  • Target Name: Human GFAT1 protein
  • Antigen: Human GFAT1 S243-phosphorylated synthetic peptide
  • Application: WB, IP
  • Target Entrez Gene ID: 2673

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunoprecipitation: 1–5 µg per reaction

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 0.5 mL (Cat.# 28123) or 1.0 mL (Cat.# 28121) H2O (final concentration 100 µg/mL).

Alternative names

glutamine:fructose 6 phosphate amidotransferase 1, hexosephosphate aminotransferase 1, D-fructose-6-phosphate amidotransferase 1, GFA, GFAT, GFPT, GFPT1, MSLG, CMSTA1, GFAT1m, GFPT1L




 
 
Products
Cat. # Product Package Size Price # of Units Select
28121A Anti-GFAT1 (663) Rabbit IgG Affinty Purify 10 ug $100.00
28121B Anti-GFAT1 (663) Rabbit IgG Affinty Purify 100 ug $499.00
28123A Anti-Human GFAT1 (S243 Phosphorylated) Rabbit IgG Affinity Purif 5 ug $100.00
28123B Anti-Human GFAT1 (S243 Phosphorylated) Rabbit IgG Affinity Purif 50 ug $499.00
 

 



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