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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_E-G >  FHIT_Human

Anti-Human FHIT (F130) Rabbit IgG Antibody

The human fragile histidine triad (FHIT) gene encodes a protein that is involved in purine metabolism. Aberrant transcripts from this gene, typically from carcinogen-induced damage and translocations, have been found in about half of all esophageal, stomach, and colon carcinomas. Although the exact function of human FHIT protein is not known, animal studies have demonstrated its role as a tumor suppressor in breast and lung cancers. FHIT protein is also known as bis(5'-adenosyl)-triphosphatase, diadenosine 5',5'''-P1,P3-triphosphate hydrolase, AP3A hydrolase, AP3Aase, dinucleosidetriphosphatase, and FRA3B.

This product is an affinity-purified IgG antibody that recognizes human FHIT protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human FHIT protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18163A, 18163B
  • Target Name: Human FHIT protein
  • Antigen: Human FHIT C-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 2272

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 5 µg/mL
  • Immunohistochemical techniques: 2–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

bis(5'-adenosyl)-triphosphatase, diadenosine 5',5'''-P1,P3-triphosphate hydrolase, AP3A hydrolase, AP3Aase, dinucleosidetriphosphatase, FRA3B




 
 
Products
Cat. # Product Package Size Price # of Units Select
18163A Anti-Human FHIT (F130) Rabbit IgG Affinity Purify 10 ug $113.00 *
18163B Anti-Human FHIT (F130) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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