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Products >  Cell_Biology >  Miscellaneous >  Primary_Antibodies_A_D >  dbpA_Human

Anti-Human dbpA Rabbit IgG Antibody

DNA binding protein A (dbpA) belongs to the Y-box binding protein family, characterized by an 80 amino-acid cold shock domain that imparts DNA-binding activity. It is also known as cold shock domain protein A (CSDA), CSDA1, ZO-1-associated nucleic acid-binding protein (ZONAB), and single-strand DNA-binding protein NF-GMB. DbpA has been reported to bind to the promoter for granulocyte-macrophage colony-stimulating factor (GM-CSF) and act as a repressor of transcription. It also binds to full-length mRNA and small RNAs containing the consensus site UCCAUCA, suggesting a role as a repressor of translation. Mutations in the CSDA gene have been associated with hepatocarcinogenesis.

This product is an affinity-purified IgG antibody that recognizes human dbpA. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human dbpA.

  At-A-Glance   Documents

Features

  • Cat.#: 18981A, 18981B
  • Target Name: Human dbpA
  • Antigen: Human dbpA C-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 8531

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunohistochemical techniques: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Cold shock domain protein A, CSDA, CSDA1, ZO-1-associated nucleic acid-binding protein, ZONAB, single-strand DNA-binding protein NF-GMB




 
 
Products
Offers Cat. # Product Contents Size Price Units Select
18981A Anti-Human dbpA Rabbit IgG Affinity Purify 10 ug $113.00 *
  18981B Anti-Human dbpA Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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