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Products >  Cell_Biology >  Metabolic_Diseases >  Antibodies >  Insulin-Mouse_Polyclonal

Anti-Mouse Proinsulin Polyclonal Antibody

Insulin is produced in a step-wise process. Preproinsulin is a biologically inactive precursor that consists of an N-terminal signal peptide followed by the proinsulin molecule. Removal of the signal peptide by signal peptidases results in proinsulin alone. Proinsulin contains the A-chain, B-chain and a 31-amino-acid Connecting peptide or C-peptide. The C-peptide is positioned between the A-chain and the B-chain and functions to connect them. The C-peptide is removed once proinsulin is processed into insulin.

Anti-mouse proinsulin polyclonal antibody, also known as anti-insulin 1 C-peptide, is frequently used to study the structure, function and metabolism of insulin as well as proinsulin. The anti-insulin 1 C-peptide can also be used for immunocytochemistry and for immunohistochemical studies of paraffin-embedded or frozen tissue sections. Mouse proinsulin polyclonal antibody is generated in Guinea pig immunized with the KLH-conjugated mouse proinsulin peptide (71-84) [SPGDLQTLALEVAR].

At-A-Glance Documents Images & Data

Applications

  • Structural, functional and metabolic analyses of proinsulin and insulin 
  • Immunocytochemistry
  • Immunohistochemistry of paraffin-embedded or frozen tissue sections

 

Storage

Lyophilized antibody is stable at 4°C for up to 2 years. The reconstituted solution can be stored at 4°C for up to 6 months or at –20°C for up to 1 year.

Notes

For research use only. Not for clinical diagnostics.

Specificity

  • This product does not cross-react with human peptide-C.

Form

Lyophilized

Reconstitution

Dissolve the lyophilized antibody in 100 µl of distilled water (final concentration: 2.0 mg/ml).




 
 
Products
Cat. # Product Package Size Price # of Units Select
M178 Anti-Mouse Insulin C, Polyclonal 0.1 mg $357.00
 

 



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