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Cell Biology

Products >  Cell_Biology >  Metabolic_Diseases >  Antibodies >  Endothelin-A_Receptor_Human

Anti-Human Endothelin-A Receptor (A405) Rabbit IgG Antibody

Endothelins are among the most potent vasoconstrictor proteins known. They are expressed in many tissues and mediate their activity through binding to two distinct endothelin receptors, known as endothelin A receptor and endothelin B receptor. The endothelin A receptor, encoded by the EDNRA gene, associates with guanine-nucleotide-binding (G) proteins; this interaction activates a phosphatidylinositol-calcium second messenger system. Endothelin A receptor binds endothelin-1 with high affinity and endothelin-2 with moderate affinity. It binds very weakly to endothelin-3. Endothelin A receptor is expressed in a variety of tissues, including lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta. Endothelin A receptor is also known as endothelin receptor type A, ET-A, ETA-R, ETRA, hET-AR, and endothelin-1 receptor.

This product is an affinity-purified IgG antibody that recognizes human endothelin A receptor. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of endothelin A receptor.

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  • Cat.#: 16201A, 16201B
  • Target Name: Human endothelin A receptor
  • Antigen: Human endothelin A receptor synthetic peptide
  • Application: WB, IHC
  • Specificity: Cross-reacts with bovine and rat endothelin A receptor
  • Target Entrez Gene ID: 1909


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 5 µg/mL
  • Immunohistochemical techniques: 5 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

Endothelin receptor type A, ET-A, ETA-R, ETRA, hET-AR, endothelin-1 receptor

Cat. # Product Contents Size Price Units Select
16201A Anti-Human Endothelin-A Receptor (A405) Rabbit IgG Affinity Purify 10 ug $113.00
16201B Anti-Human Endothelin-A Receptor (A405) Rabbit IgG Affinity Purify 100 ug $499.00



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