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Products >  Cell_Biology >  Metabolic_Diseases >  Antibodies >  Adiponectin_Receptor_2_Human

Anti-Human Adiponectin Receptor 2 Rabbit IgG Antibody

Anti-Human Adiponectin Receptor 2 Antibody is an affinity-purified IgG antibody that recognizes the human adiponectin receptor 2 (ADIPOR2) protein. The antibody was raised in rabbit using a synthetic peptide and can be detected through Western blot analysis of human ADIPOR2 protein.

Human adiponectin is a protein hormone secreted by adipocytes and is involved in several metabolic functions, including the regulation of glucose levels and fatty acid metabolism. Two receptors for adiponectin have been identified with homology to the G protein-coupled receptors (GPCRs): ADIPOR1 and ADIPOR2. Similar to GPCRs, ADIPOR2 also possesses seven transmembrane domains. However, ADIPOR2 is not known to associate with G proteins. Binding of adiponectin to ADIPOR2 mediates increased AMP-activated protein kinase (AMPK) activity, peroxisome proliferator-activated receptor-alpha (PPAR-alpha) ligand activity, fatty acid oxidation, and glucose uptake. ADIPOR2 is also known as progestin and adipoQ receptor family member II (PAQR2), and ACDCR2.

  At-A-Glance   Documents

Features

Cat.#: 18995A, 18995B

  • Target Name: Human ADIPOR2 protein
  • Antigen: Human ADIPOR2 synthetic peptide
  • Application: Western blot
  • Specificity: Cross-reacts with mouse ADIPOR2; does not cross-react with ADIPOR1
  • Target Entrez Gene ID: 79602

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL

Storage

Lyophilized: stable up to 5 years at 2–8°C. In solution: stable up to 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

ADIPOR2, progestin and adipoQ receptor family member II, PAQR2, ACDCR2




 
 
Products
Cat. # Product Contents Size Price Units Select
18995A Anti-Human Adiponectin Receptor 2 Rabbit IgG Affinity Purify 10 ug $113.00 *
18995B Anti-Human Adiponectin Receptor 2 Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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