Takara
login | register | order now | view cart | feedback
Products
Cell Biology


Products >  Cell_Biology >  Epigenetics >  Antibodies >  NP95_Human_Monoclonal

Anti-Human NP95 (mt40) Mouse IgG MoAb

Human nucleoprotein 95 (NP95) is a member of a subfamily of RING-finger type E3 ubiquitin ligases and is encoded by the UHRF1 gene in humans. NP95 binds specifically to DNA and recruits a histone deacetylase to regulate gene expression. NP95 expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase II alpha and retinoblastoma (Rb) gene expression. NP95 also functions in the p53-dependent response to DNA damage, and its expression is upregulated in lymphomas induced by radiation. NP95 is also known as ubiquitin-like with PHD and ring finger domains 1 (UHRF1), ubiquitin-like PHD and RING finger domain-containing protein 1, RING finger protein 106 (RNF106), inverted CCAAT box-binding protein of 90 kDa (ICBP90), nuclear zinc finger protein Np95, E3 ubiquitin-protein ligase UHRF1, hUHRF1, hNP95, HuNp95, and FLJ21925.

This product is an affinity-purified IgG antibody that recognizes human NP95 protein. The antibody was raised in mouse using purified NP95 and can be used for Western blot (WB) detection of human NP95 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 10371A, 10371B
  • Target Name: Human NP95 protein
  • Antigen: Purified human NP95 protein
  • Application: WB
  • Target Entrez Gene ID: 29128

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–10 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Ubiquitin-like with PHD and ring finger domains 1, UHRF1, ubiquitin-like PHD and RING finger domain-containing protein 1, RING finger protein 106, RNF106, inverted CCAAT box-binding protein of 90 kDa, ICBP90, nuclear zinc finger protein Np95, E3 ubiquitin-protein ligase UHRF1, hUHRF1, hNP95, HuNp95, FLJ21925




 
 
Products
Cat. # Product Package Size Price # of Units Select
10371A Anti-Human NP95 (mt40) Mouse IgG MoAb 10 ug $113.00 *
10371B Anti-Human NP95 (mt40) Mouse IgG MoAb 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 



Clontech is a Takara Bio Company © 2014 Privacy Policy | Terms & Conditions