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Products >  Cell_Biology >  Cytokines >  Antibodies_H-T >  NFkappB_p50_Human

Anti-Human NF-kappaB p50 Rabbit IgG Antibody

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) is a ubiquitous transcription factor that was identified based on its interaction with an 11-base pair sequence in the immunoglobulin light-chain enhancer in B cells. NF-kappaB is involved in a variety of signaling processes, including responses to stress, cytokines, free radicals, ultraviolet radiation, and bacterial and viral antigens. NF-kappaB consists of two subunits, each of which can exist as multiple isoforms. In humans, a 105 kDa precursor is encoded by the NFKB1 gene, and is processed into a 50 kDa protein known as NF-kappaB p50. This subunit can form homodimers, or heterodimers with other subunits; the most abundant NF-kappaB form consists of a p50-p65 heterodimer. NF-kappaB p50 is also known as NFKB1, NFKB-p50, KBF1, EBP-1, DNA-binding factor KBF1, and nuclear factor NF-kappa-B p50 subunit.

These products are affinity-purified IgG antibodies that recognize human NF-kappaB p50 protein. The antibodies were raised in rabbit using synthetic peptides, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of NF-kappaB p50 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18661A, 18661B
  • Target Name: Human NF-kappaB p50 protein
  • Antigen: Human NF-kappaB p50 N-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 4790

  • Cat.#: 18663A, 18663B
  • Target Name: Human NF-kappaB p50 protein
  • Antigen: Human NF-kappaB p50 C-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 4790

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunoprecipitation: 5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

NFKB1, NFKB-p50, KBF1, EBP-1, DNA-binding factor KBF1, nuclear factor NF-kappa-B p50 subunit




 
 
Products
Cat. # Product Package Size Price # of Units Select
18661A Anti-Human NFkappaB p50 (N) Rabbit IgG Affinity Purify 10 ug $113.00 *
18661B Anti-Human NFkappaB p50 (N) Rabbit IgG Affinity Purify 100 ug $499.00
18663A Anti-Human NFkappaB p50 (C) Rabbit IgG Affinity Purify 10 ug $113.00 *
18663B Anti-Human NFkappaB p50 (C) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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