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Products >  Cell_Biology >  Cytokines >  Antibodies_H-T >  IL-6_Rat

Anti-Rat IL-6 (N) Rabbit IgG Antibody

Interleukins are a group of cytokines that were originally identified in white blood cells (leukocytes). It is now known that interleukins are expressed in a wide variety of cells, and are involved in multiple cell signaling pathways. Interleukin 6 (IL-6) is a cytokine that is involved in a wide variety of biological functions, including the inflammatory response and the maturation of B cells. It acts on B cells, T cells, hepatocytes, hematopoietic progenitor cells, and cells of the central nervous system (CNS). IL-6 is expressed at sites of acute and chronic inflammation, where it is secreted into the serum and binds the IL-6 receptor alpha. Studies have demonstrated that, in humans, IL-6 also acts as an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The IL-6 gene has been implicated in many inflammation-associated disease states, including diabetes mellitus and juvenile rheumatoid arthritis. IL-6 is also known as interferon beta-2 (IFNB2), B-cell stimulatory factor-2 (BSF-2), CTL differentiation factor (CDF), B-cell stimulatory factor 2 (BSF2), B-cell differentiation factor, and hybridoma growth factor (HGF).

This product is an affinity-purified IgG antibody that recognizes rat IL-6 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of rat IL-6 protein.

  At-A-Glance   Documents

Features

  • Cat.#: 18611A, 18611B
  • Target Name: Rat IL-6 protein
  • Antigen: Rat IL-6 N-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 24498

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 2–5 µg/mL
  • Immunohistochemical techniques: 5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

Interferon beta-2, IFNB2, B-cell stimulatory factor-2, BSF-2, CTL differentiation factor, CDF, B-cell stimulatory factor 2, BSF2, B-cell differentiation factor, hybridoma growth factor, HGF




 
 
Products
Cat. # Product Contents Size Price Units Select
18611A Anti-Rat IL-6 (N) Rabbit IgG Affinity Purify 10 ug $113.00 *
18611B Anti-Rat IL-6 (N) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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