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Products >  Cell_Biology >  Cytokines >  Antibodies_H-T >  IL-1_Beta_Rat

Anti-Rat IL-1 Beta (C) Rabbit IgG Antibody

Interleukins are a group of cytokines that were originally identified in white blood cells (leukocytes). It is now known that interleukins are expressed in a wide variety of cells, and are involved in multiple cell signaling pathways. Interleukin 1 (IL-1) alpha and beta participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis. IL-1 beta is produced primarily in activated macrophages by proteolytic cleavage of an inactive precursor by caspase 1. It also plays a role in memory functions and regulation of the central nervous system (CNS), as well as in cell proliferation, differentiation, and apoptosis. IL-1 beta acts through two main receptors that also bind IL-1 alpha. IL-1 beta is also known as catabolin, IL1B, and IL1F2.

This product is an affinity-purified IgG antibody that recognizes rat IL-1 beta protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of rat IL-1 beta protein.

At-A-Glance Documents

Features

  • Cat.#: 18141A, 18141B
  • Target Name: Rat IL-1 beta protein
  • Antigen: Rat IL-1 beta C-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 24494

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.5–5.0 µg/mL
  • Immunohistochemical techniques: 5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

catabolin, IL1B, IL1F2




 
 
Products
Cat. # Product Package Size Price # of Units Select
18141A Anti-Rat IL-1 beta (C) Rabbit IgG Affinity Purify 10 ug $100.00
18141B Anti-Rat IL-1 beta (C) Rabbit IgG Affinity Purify 100 ug $499.00
 

 



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