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Products >  Cell_Biology >  Cytokines >  Antibodies_D-G >  GRO_CINC-1_Rat

Anti-Rat GRO/CINC-1 Antibody

Rat cytokine-induced neutrophil chemoattractant-1 (CINC-1) protein is a member of the CXC family of chemokines. The rat CINC family members, including CINC-1, CINC-2-alpha, CINC-2-beta, and CINC-3, are homologous to human GRO/CXCL and mouse MIP-2/KC genes. Rat CINC-1 is also known as chemokine (C-X-C motif) ligand 1 (CXCL1), GRO-alpha, and melanoma growth stimulating activity alpha (MGSA alpha). In addition to its established role as a neutrophil chemoattractant, CINC-1 functions as an early acute-phase protein. Levels of CINC-1 in the liver and serum rise in response to brain injury, and CINC-1 is suggested to be responsible for recruitment of neutrophils to the site of injury.

These products are antibodies that recognize rat CINC-1 protein. The antibodies were raised in either mouse or rabbit using synthetic peptides, and can be used for Western blot (WB) detection, neutralization tests (NT), or immunohistochemical (IHC) detection of rat CINC-1 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 10071A
  • Target Name: Rat CINC-1 protein
  • Antigen: Rat CINC-1 C-terminal synthetic peptide
  • Clone: 6G2
  • Specificity: Does not cross-react with N-terminal rat CINC-1, rat CINC-2-alpha, rat CINC-2-beta, rat CINC-3, mouse MIP-2, human GRO-alpha, or human IL-8
  • Application: WB
  • Target Entrez Gene ID: 81503

  • Cat.#: 10072A, 10072B
  • Target Name: Rat CINC-1 protein
  • Antigen: Rat CINC-1 N-terminal synthetic peptide
  • Clone: 2A9
  • Specificity: Does not cross-react with C-terminal rat CINC-1, rat CINC-2-alpha, rat CINC-2-beta, rat CINC-3, mouse MIP-2, human GRO-alpha, or human IL-8
  • Application: WB, NT
  • Target Entrez Gene ID: 81503

  • Cat.#: 18251A, 18251B
  • Target Name: Rat CINC-1 protein
  • Antigen: Rat CINC-1 complete synthetic peptide
  • Specificity: Cross-reacts with mouse KC; does not cross-react with rat CINC-2-alpha, rat CINC-2-beta, rat CINC-3, or mouse MIP-2
  • Application: WB, IHC
  • Target Entrez Gene ID: 81503

  • Cat.#: 18256B
  • Target Name: Rat CINC-1 protein
  • Antigen: Rat CINC-1 C-terminal synthetic peptide
  • Specificity: Does not cross-react with rat CINC-2-alpha, rat CINC-2-beta, or rat CINC-3
  • Application: WB, NT
  • Target Entrez Gene ID: 81503

  • Cat.#: 18257A, 18257B
  • Target Name: Rat CINC-1 protein
  • Antigen: Rat CINC-1 N-terminal synthetic peptide
  • Specificity: Does not cross-react with rat CINC-2-alpha, rat CINC-2-beta, or rat CINC-3
  • Application: WB, NT, IHC
  • Target Entrez Gene ID: 81503

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 5–10 µg/mL (Cat.# 10071); 2–5 µg/mL (Cat.# 10072, 18256, 18257); 10–20 µg/mL (Cat.# 18251)
  • Neutralization test: 100 µg/mL (Cat.# 10072); 1010 µg/mL (Cat.# 18256); 10 µg/mL (Cat.#18257)
  • Immunohistochemical techniques: 10–20 µg/mL (Cat.# 18251); 2–5 µg/mL (Cat.# 18257)

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing PBS. To use, reconstitute in 1.0 mL H2O.

Alternative names

Chemokine (C-X-C motif) ligand 1, CXCL1, cytokine-induced neutrophil chemoattractant-1, CINC-1, GRO-alpha, melanoma growth stimulating activity alpha, MGSA alpha




 
 
Products
Cat. # Product Package Size Price # of Units Select
10071A Anti-Rat GRO/CINC-1 (6G2) (C) Mouse IgM MoAb 500 ug $499.00
10072A Anti-Rat GRO/CINC-1 (2A9) (N) Mouse IgG MoAb 10 ug $100.00
10072B Anti-Rat GRO/CINC-1 (2A9) (N) Mouse IgG MoAb 500 ug $499.00
18256B Anti-Rat GRO/CINC-1 (C) Rabbit IgG Affinity Purify 100 ug $499.00
18257A Anti-Rat GRO/CINC-1 (N) Rabbit IgG Affinity Purify 10 ug $100.00
18257B Anti-Rat GRO/CINC-1 (N) Rabbit IgG Affinity Purify 100 ug $499.00
18251A Anti-Rat GRO/CINC-1 Rabbit IgG 25 ug $100.00
18251B Anti-Rat GRO/CINC-1 Rabbit IgG 500 ug $499.00
 

 



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