Fibronectin-Related Peptide (GRGDSP) contains the RGD cell binding domain, enabling it to bind to fibronectin receptors. This peptide may be used to inhibit fibronectin binding. Fibronectin-Related Peptide (GRGESP) contains an aspartic acid (E) in place of glutamic acid (D). This single amino acid change results in an inability to bind to fibronectin receptors, making it a suitable control for cell-adhesion experiments with fibronectin.
