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Products >  Cell_Biology >  Cell_Adhesion_and_Extracellular_Matrix >  Antibodies_D_N >  N-Cadherin_Human

Anti-Human N-Cadherin Rabbit IgG Antibody

Cadherins, a family of calcium-dependent intracellular adhesion glycoproteins, play an important role in cell-cell interaction, histogenesis and cellular transformation. N-cadherin, also known as cadherin 2 (CDH2), CDHN, NCAD, CD325, and CDw325, contains five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. It plays an essential role in gastrulation and is required for establishment of left-right asymmetry. The interaction of N-cadherin with intracellular catenin proteins contributes to learning and memory processes.

These products are affinity-purified IgG antibodies that recognizes human N-cadherin protein. The antibodies were raised in rabbit using recombinant protein (Cat.# 18571) or synthetic peptide (Cat.# 18573, 18574) and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human N-cadherin protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18571A, 18571B
  • Target Name: Human N-cadherin protein
  • Antigen: Recombinant human N-cadherin protein (extracellular subdomain 1-3)
  • Clone: YS
  • Application: WB, IHC, IP
  • Specificity: Does not cross-react with other cadherins
  • Target Entrez Gene ID: 1000

  • Cat.#: 18573A
  • Target Name: Human N-cadherin protein
  • Antigen: Human N-cadherin (212-225) synthetic peptide
  • Clone: 224
  • Application: IHC
  • Specificity: Human N-cadherin
  • Target Entrez Gene ID: 1000

  • Cat.#: 18574A
  • Target Name: Human N-cadherin protein
  • Antigen: Human N-cadherin (746-761) synthetic peptide
  • Clone: 760
  • Application: IHC
  • Specificity: Human N-cadherin
  • Target Entrez Gene ID: 1000

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.5–2.0 µg/mL
  • Immunohistochemical techniques: 1-5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing PBS (Cat.# 18571A, 18571B); 1% BSA in PBS and 0.05% NaN3 (Cat.# 18573A, 18574A). To use, reconstitute in 1.0 mL H2O.

Alternative names

Cadherin 2, CDH2, CDHN, NCAD, CD325, CDw325




 
 
Products
Cat. # Product Package Size Price # of Units Select
18571A Anti-Human N-Cadherin (YS) Rabbit IgG Affinity Purify 10 ug $100.00
18571B Anti-Human N-Cadherin (YS) Rabbit IgG Affinity Purify 100 ug $499.00
18573A Anti-Human N-Cadherin (224) Rabbit IgG Affinity Purify 100 ug $499.00
18574A Anti-Human N-Cadherin (760) Rabbit IgG Affinity Purify 100 ug $499.00
 

 



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