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Cell Biology

Products >  Cell_Biology >  Cell_Adhesion_and_Extracellular_Matrix >  Antibodies_A_C >  Claudin-1_Mouse_Rat_Antibody

Anti-Mouse/Rat Claudin-1 (C) Rabbit IgG Antibody

Claudins are a family of proteins that control the flow of molecules in the intercellular space between epithelial cells. They are the most important components of tight junctions--a form of cell-to-cell adhesion that forms continuous seals around cells. Tight junctions act as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Claudins have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Over 24 members of the claudin family have been identified in humans. In mouse, claudin-1, -2, -6, -7, and -15 are expressed at high levels in liver and kidney, while claudin-5 is expressed in vascular endothelial cells. Claudin-1 is also known as CLD1, senescence-associated epithelial membrane protein 1 (SEMP1), and ILVASC.

This product is an affinity-purified IgG antibody that recognizes mouse/rat claudin-1 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, and immunocytochemical (ICC) detection of mouse/rat claudin-1 protein.

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  • Cat.#: 18815A, 18815B
  • Target Name: Mouse/rat claudin-1 protein
  • Antigen: Mouse/rat claudin-1 C-terminal synthetic peptide
  • Application: WB, IHC, ICC
  • Specificity: Reacts with claudin-1; does not cross-react with claudins 2-8
  • Target Entrez Gene ID: 12737, 65129


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 2 µg/mL
  • Immunohistochemical/immunocytochemical techniques: 5 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

CLD1, senescence-associated epithelial membrane protein 1, SEMP1, ILVASC

Cat. # Product Contents Size Price Units Select
18815A Anti-Mouse/Rat Claudin-1 (C) Rabbit IgG Affinity Purify 10 ug $113.00
18815B Anti-Mouse/Rat Claudin-1 (C) Rabbit IgG Affinity Purify 100 ug $499.00



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