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Products >  Cell_Biology >  Cell_Adhesion_and_Extracellular_Matrix >  Antibodies_A_C >  Calpastatin_Human_Monoclonal

Human Calpastatin Antibody (Monoclonal)

Calpastatin (CAST) is a calpain inhibitor, a calcium-dependent cysteine protease that is widely distributed in higher order animals. There are different types of calpastatins; examples include the 68 kDa erythrocyte-derived calpastatin and the 107 kDa myocyte-derived calpastatin (as evidenced by SDS-PAGE). Through its inhibition of calpain, calpastatin is believed to play important roles in the regulation of cell proliferation, differentiation and aging. CAST is also involved in the proteolysis of amyloid precursor protein (APP). 

Human Calpastatin Antibody (Monoclonal) (CSL1-5 clone) is raised against recombinant myocyte-derived calpastatin.

At-A-Glance Documents Images & Data Resources

Features

  • Sensitive and specific human calpastatin detection

Applications

  • Measurement of calpastatin levels in cell culture supernatant
  • Western blot analysis under reducing and non-reducing conditions

Source

CloneCat.#ImmunogenImmunized hostSubclassAntibody titer
CSL1-5M045Human calpastatinBALB/c mouseIgG11:4,000

Storage

4°C


Stock solution (2.0 mg/mL) aliquots should be stored at -20°C for up to 1 year, or at 4°C for up to 6 months.

Notes

For research use only. Not intended for clinical diagnostic use.

Specificity

This antibody specifically reacts with human calpastatin.

Form

Lyophilized

Reconstitution

Dissolve lyophilized antibody in 50 µL of distilled water (final concentration: 2.0 mg/mL).

References

  1. Asada, K. et al. (1989) J. Enzyme Inhib. 3:49.
  2. Towbin, H. et al. (1979) Proc. Natl. Acad. Sci. USA 76:4350.
  3. Engvall, E. & Perlmann, P. (1972) J. Immunol. 109:129.
  4. Uemori, T. et al. (1990) Biochem. Biophys. Res. Comm. 166:1485-1493.
  5. Yokota, H. et al. (1991) Mol. Cell. Probes 5:261-269.



 
 
Products
Cat. # Product Package Size Price # of Units Select
M045 Monoclonal Anti-Human Calpastatin (Clone CSL1-5) 0.1 mg $357.00
 

 


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