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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_T-Z >  Tob

Anti-Human Tob Rabbit IgG Antibody

Transducer of ErbB-2, 1 (TOB1) is an antiproliferative factor that belongs the tob/btg1 family. TOB1 and TOB2 have the ability to suppress cell growth in cell culture. TOB1 is phosphorylated by ribosomal S6 serine/threonine kinase. It interacts with ErbB-2 and interferes with growth suppression in B cells. TOB1 also inhibits T cell proliferation and the transcription of some cytokines, including interleukin 2 (IL-2). TOB1 is also known as TROB1, TROB, TOB, APRO6, and proliferation-inducing gene 49 (PIG49).

These products are affinity-purified IgG antibodies that recognize human TOB1 protein. The antibodies were raised in rabbit or mouse using recombinant protein or a synthetic peptide and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human TOB1 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 10031A, 10031B
  • Target Name: Human TOB1 protein
  • Antigen: Human TOB1 recombinant protein
  • Application: WB, IHC
  • Target Entrez Gene ID: 10140

  • Cat.#: 18911A
  • Target Name: Human TOB1 protein
  • Antigen: Human TOB1 (phosphorylated) synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 10140

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1 µg/mL (Cat.# 10031); 2 µg/mL (Cat.# 18911)
  • Immunohistochemical techniques: 1–3 µg/mL (Cat.# 10031); 5 µg/mL (Cat.# 18911)

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

Transducer of ErbB-2, 1; TROB1, TROB, TOB, APRO6, proliferation-inducing gene 49, PIG49




 
 
Products
Cat. # Product Package Size Price # of Units Select
10031A Anti-Tob (4B1) Mouse IgG MoAb 10 ug $113.00 *
10031B Anti-Tob (4B1) Mouse IgG MoAb 200 ug $499.00
18911A Anti-Human Tob (Phosphorylated) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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