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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_T-Z >  Tenascin-C_Human_Monoclonal

Anti-Human Tenascin-C Mouse IgG MoAb

Tenascin-C is a multifunctional extracellular matrix glycoprotein that contains multiple subunits with molecular weights of 210-400 kDa. These subunits include several repeated motifs with similarity to epidermal growth factor (EGF), fibronectin type III (FNIII), and the globular domain of the beta and gamma chains of fibrinogen. Tenascin-C is a ligand that binds to several integrin receptors. During embryonic development, tenascin-C is involved in guidance of migrating neurons and axons, synaptic plasticity, and neuronal regeneration. Studies in adults have suggested that tenascin-C is upregulated during oncogenesis, arthritis, and liver and lung fibrosis. Tenascin-C is also known as cytotactin, hexabrachion, myotendinous antigen, neuronectin, glioma-associated-extracellular matrix antigen, HXB, TN, TN-C, J1, MGC167029, and GMEM.

These products are affinity-purified IgG antibodies that recognize human tenascin-C protein. The antibodies were raised in mouse using human tenascin-C protein and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human tenascin-C protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 10335A, 10335B
  • Target Name: Human tenascin-C protein
  • Antigen: Human tenascin-C (domain B, FNIII repeats) recombinant protein
  • Clone: 4C8MS
  • Specificity: Cross-reacts with mouse and rat tenascin-C
  • Application: WB, IHC
  • Target Entrez Gene ID: 3371

  • Cat.#: 10337A, 10337B
  • Target Name: Human tenascin-C protein
  • Antigen: Human tenascin-C protein (EGF-like domain)
  • Clone: 4F10TT
  • Specificity: Cross-reacts with mouse, rat, chicken, and rabbit tenascin-C
  • Application: WB, IHC
  • Target Entrez Gene ID: 3371

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 5 µg/mL (Cat.# 10335); 1 µg/mL (Cat.# 10337)
  • Immunohistochemical techniques: 5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Cytotactin, hexabrachion, myotendinous antigen, neuronectin, glioma-associated-extracellular matrix antigen, HXB, TN, TN-C, J1, MGC167029, GMEM




 
 
Products
Cat. # Product Package Size Price # of Units Select
10335A Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb 10 ug $100.00
10335B Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb 100 ug $499.00
10337A Anti-Human Tenascin-C (EGF Like Domain) (4F10TT) Mouse IgG MoAb 10 ug $100.00
10337B Anti-Human Tenascin-C (EGF Like Domain) (4F10TT) Mouse IgG MoAb 100 ug $499.00
 

 



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