Home Takara Clontech Logo Takara Clontech
login | register | order now | view cart | feedback
Products
Cell Biology


Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_T-Z >  TEK-Tie-2_Human_Monoclonal

Anti-Human TEK/Tie-2 (2A1) Mouse IgG MoAb

The endothelial tyrosine kinase TEK is a cell-surface receptor that binds the growth factor angiopoietin-1. It is closely related to the TIE receptor tyrosine kinase. TEK-mediated signaling regulates angiogenesis, reorganization of the actin cytoskeleton, and survival, proliferation, migration, adhesion, and spreading of endothelial cells. Activation of TEK leads to downstream activation of MAPK1/ERK2 and MAPK3/ERK1 kinases. Mutations in the TEK gene are associated with inherited venous malformations. TEK is also known as TEK tyrosine kinase, endothelial; endothelial tyrosine kinase, Tunica interna endothelial cell kinase, tyrosine kinase with Ig and EGF homology domains-2 (TIE-2), hTIE2, p140 TEK, CD202b, angiopoietin-1 receptor, VMCM, and VMCM1.

This product is an affinity-purified IgG antibody that recognizes TEK/TIE-2 protein. The antibody was raised in mouse using recombinant TEK/TIE-2 protein and can be used for Western blot (WB) detection, immunocytochemical (ICC) detection, immunoprecipitation (IP), or flow cytometry (FCM) of human TEK/TIE-2 protein.

  At-A-Glance   Documents   Images & Data

Features

  • Cat.#: 10369A, 10369B
  • Target Name: Human TEK/TIE-2 protein
  • Antigen: Human TEK/TIE-2 (extracellular domain) recombinant protein
  • Application: WB, ICC, IP, FCM
  • Target Entrez Gene ID: 7010

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunocytochemical techniques: 5 µg/mL
  • Immunoprecipitation: 3–5 µg per reaction
  • Flow cytometry: 1–5 µg per 1 x 105 cells

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

TEK tyrosine kinase, endothelial; endothelial tyrosine kinase, Tunica interna endothelial cell kinase, tyrosine kinase with Ig and EGF homology domains-2, TIE-2, hTIE2, p140 TEK, CD202b, angiopoietin-1 receptor, VMCM, VMCM1




 
 
Products
Cat. # Product Contents Size Price Units Select
10369A Anti-Human TEK/Tie-2 (2A1) Mouse IgG MoAb 10 ug $113.00
10369B Anti-Human TEK/Tie-2 (2A1) Mouse IgG MoAb 100 ug $499.00
 

 

 
 

Clontech is a Takara Bio Company © 2015 Privacy Policy | Terms & Conditions