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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_O-S >  SP-A_Human_Monoclonal

Anti-Human SP-A (PE10) Mouse IgG MoAb

Surfactant protein A1 (SP-A or SP-A1) is a member of the C-type lectin family of proteins, known as collectins. In humans, it is encoded by the SFTPA1 gene. SP-A is the major protein component of pulmonary surfactant, a lipoprotein complex secreted by the alveolar type II cell. Pulmonary surfactant reduces surface tension in the alveolus and prevents alveolar collapse during exhalation. In addition to its role as a surfactant, SP-A modulates the alveolar immune response to microbes and inhaled particulate matter. SP-A is also expressed in nonalveolar cells, and is thought to be involved in functions such as immune cell proliferation, stimulation of proinflammatory cytokine expression, and control of reactive oxygen species. Mutations in the SFTPA1 gene are associated with idiopathic pulmonary fibrosis. SP-A is also known as alveolar proteinosis protein, 35 kDa pulmonary surfactant-associated protein, pulmonary surfactant-associated protein A1, surfactant protein A1B, collectin-4, SP-A1, PSAP, PSPA, SFTP1, SFTPA, SPA, SPA1, COLEC4, and SFTPA1B.

This product is an affinity-purified IgG antibody that recognizes human SP-A protein. The antibody was raised in mouse using purified SP-A protein and can be used for immunohistochemical (IHC) detection of human SP-A protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 10375A, 10375B
  • Target Name: Human SP-A protein
  • Antigen: Human SP-A purified protein
  • Application: IHC
  • Target Entrez Gene ID: 653509

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Immunohistochemical techniques: 5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Alveolar proteinosis protein, 35 kDa pulmonary surfactant-associated protein, pulmonary surfactant-associated protein A1, surfactant protein A1B, collectin-4, SP-A1, PSAP, PSPA, SFTP1, SFTPA, SPA, SPA1, COLEC4, SFTPA1B




 
 
Products
Cat. # Product Package Size Price # of Units Select
10375A Anti-Human SP-A (PE10) Mouse IgG MoAb 50 ug $100.00
10375B Anti-Human SP-A (PE10) Mouse IgG MoAb 500 ug $535.00
 

 



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