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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_A-G >  c-Met_Beta_Human_Antibody

Human c-Met beta (HGFR) Antibody

The c-Met proto-oncogene encodes a protein known as hepatocyte growth factor receptor (HGFR). HGFR is also known as RCCP2, scatter factor (SF) receptor, HGF/SF receptor, and AUTS9. HGFR possesses tyrosine-kinase activity. The HGFR precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are linked by disulfide bonds to form the mature HGFR protein. Abnormal expression of c-Met results in tumor growth, angiogenesis, and metastasis.

These products are affinity-purified IgG antibodies that recognize human HGFR protein. The antibodies were raised in rabbit using synthetic peptides and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human HGFR or phosphorylated HGFR (Tyr1235).

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Features

  • Cat.#: 18321A, 18321B
  • Target Name: Human HGFR
  • Antigen: Human HGFR (beta subunit) C-terminal synthetic peptide
  • Application: WB, IHC
  • Specificity: HGFR beta subunit
  • Target Entrez Gene ID: 4233

  • Cat.#: 28083A, 28083B
  • Target Name: Human HGFR
  • Antigen: Human HGFR (Tyr1235 phosphorylated) synthetic peptide (YDKEY(pY)SVHNK)
  • Application: WB, IHC
  • Specificity: HGFR (Tyr1235 phosphorylated)
  • Target Entrez Gene ID: 4233

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 2–5 µg/mL (Cat.# 18321);  2 µg/mL (Cat.# 28083)
  • Immunohistochemical techniques: 2–5 µg/mL (Cat.# 18321);  0.5–1 µg/mL (Cat.# 28083)

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

HGFR, RCCP2, scatter factor receptor, SF receptor, HGF/SF receptor, AUTS9




 
 
Products
Offers Cat. # Product Contents Size Price Units Select
18321A Anti-Human c-Met beta Rabbit IgG Affinity Purify 10 ug $113.00 *
  18321B Anti-Human c-Met beta Rabbit IgG Affinity Purify 100 ug $499.00
28083A Anti-c-Met (Y1235 Phosphorylated) Rabbit IgG Affinity Purify 5 ug $114.00 *
28083B Anti-c-Met (Y1235 Phosphorylated) Rabbit IgG Affinity Purify 50 ug $525.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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