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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_A-G >  Galectin-3_Human_Monoclonal

Anti-Human Galectin-3 Mouse IgG MoAb

Galectin-3 is a member of the lectin family of carbohydrate-binding proteins. In humans, it is encoded by the LGALS3 gene, and is approximately 30 kDa in size. Galectin-3 has a N-terminal proline-rich tandem repeat domain, which allows it to self-associate, and a single C-terminal carbohydrate recognition domain. It binds beta-galactoside and IgE, and is involved in a broad range of functions, including apoptosis, innate immunity, cell adhesion, chemoattraction, cell growth and differentiation, and T-cell regulation. Galectin-3 expression is implicated in processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and ventricular remodeling. Elevated levels of galectin-3 are also associated with cancer and inflammation. Galectin-3 is also known as lectin, galactoside-binding, soluble, 3; carbohydrate-binding protein 35, galactose-specific lectin 3, laminin-binding protein, lectin L-29, Mac-2 antigen, IgE-binding protein, L31, GAL3, MAC2, CBP35, GALBP, GALIG, and LGALS2.

These products are affinity-purified IgG antibodies that recognize human galectin-3 protein. The antibodies were raised in mouse using recombinant protein, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or flow cytometry (FCM) of human galectin-3 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 11100A, 11100B
  • Target Name: Human galectin-3 protein
  • Antigen: Human galectin-3 recombinant protein
  • Clone: 38B2
  • Application: WB, IHC
  • Target Entrez Gene ID: 3958

  • Cat.#: 11102A, 11102B
  • Target Name: Human galectin-3 protein
  • Antigen: Human galectin-3 recombinant protein
  • Clone: 87B5
  • Application: WB, FCM
  • Target Entrez Gene ID: 3958

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 2–5 µg/mL
  • Immunohistochemical techniques: 2–5 µg/mL
  • Flow cytometry: 2–10 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Lectin, galactoside-binding, soluble, 3; carbohydrate-binding protein 35, galactose-specific lectin 3, laminin-binding protein, lectin L-29, Mac-2 antigen, IgE-binding protein, L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2




 
 
Products
Cat. # Product Package Size Price # of Units Select
11100A Anti-Human Galectin-3 (38B2) Mouse IgG MoAb 10 ug $113.00 *
11100B Anti-Human Galectin-3 (38B2) Mouse IgG MoAb 100 ug $499.00
11102A Anti-Human Galectin-3 (87B5) Mouse IgG MoAb 10 ug $113.00 *
11102B Anti-Human Galectin-3 (87B5) Mouse IgG MoAb 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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