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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_A-G >  FAS_Human

Anti-Human Fatty Acid Synthase (FAS) Antibody

Fatty acid synthase (FAS) is a multifunctional protein, whose primary role is the NADPH-mediated synthesis of palmitate from acetyl-CoA and malonyl-CoA, into long-chain saturated fatty acids. The protein consists of two identical, multifunctional 272 kDa polypeptides. FAS is expressed at high levels in liver, brain, breast, and lung. Studies have reported the in-frame fusion of FAS with estrogen receptor alpha in some cancer cell lines, and FAS expression is upregulated in breast cancer. FAS is also known as OA-519, SDR27X1, and short chain dehydrogenase/reductase family 27X, member 1.

These products are affinity-purified IgG antibodies that recognizes human FAS protein. The antibodies were raised in mouse (Cat.# 10038) or rabbit (Cat.# 18341) using synthetic peptides, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human FAS protein.

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Features

  • Cat.#: 10038A, 10038B
  • Target Name: Human FAS protein
  • Antigen: Human FAS synthetic peptide
  • Application: WB, IHC
  • Specificity: FAS-specific, but may stain macrophages in IHC
  • Target Entrez Gene ID: 2194

  • Cat.#: 18341A, 18341B
  • Target Name: Human FAS protein
  • Antigen: Human FAS synthetic peptide
  • Application: WB, IHC
  • Specificity: FAS-specific, not tested in mouse or rat
  • Target Entrez Gene ID: 2194

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL (Cat.# 10038); 2–5 µg/mL (Cat.# 18341)
  • Immunohistochemical techniques: 1–5 µg/mL (Cat.# 10038); 2–5 µg/mL (Cat.# 18341)

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

OA-519, SDR27X1, short chain dehydrogenase/reductase family 27X member 1




 
 
Products
Cat. # Product Contents Size Price Units Select
10038A Anti-Human Fatty Acid Synthase (FAS) (14G5) Mouse IgG MoAb 10 ug $113.00 *
10038B Anti-Human Fatty Acid Synthase (FAS) (14G5) Mouse IgG MoAb 100 ug $499.00
18341A Anti-Human Fatty Acid Synthase (FAS) Rabbit IgG Affinity Purify 10 ug $113.00 *
18341B Anti-Human Fatty Acid Synthase (FAS) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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