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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_A-G >  ERK_Human_Monoclonal

Anti-Human ERK (Clone 5) Mouse IgG MoAb

Extracellular-signal-regulated kinases (ERKs), also called mitogen-activated protein kinases (MAPKs), are widely expressed signaling proteins that regulate meiosis, mitosis, and postmitotic functions in differentiated cells. Following activation by upstream kinases, ERKs are translocated to the nucleus, where they perform their regulatory functions. Disruption of ERK-mediated pathways is common in many cancers. Two members of this family were originally identified with 85% sequence similarity, called ERK1 and ERK2. ERK1 is also known as MAPK3, extracellular signal-regulated kinase 1, insulin-stimulated MAP2 kinase, microtubule-associated protein 2 kinase, PRKM3, ERT2, p44-ERK1, p44-MAPK, HS44KDAP, HUMKER1A, MAP kinase 1, and MAPK1. ERK2 is also known as MAPK1, extracellular signal-regulated kinase 2, PRKM1, PRKM2, ERT1, p41-ERK1, p41-MAPK, p42-MAPK, MAP kinase 1, MAP kinase 2, MAPK1, MAPK2, p38, p40, and p41.

This product is an affinity-purified IgG antibody that recognizes human ERK1 and ERK2 proteins. The antibody was raised in mouse using a recombinant protein, and can be used for Western blot (WB) detection of human ERK1 and ERK2 proteins.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 10359A, 10359B
  • Target Name: Human ERK1 and ERK2 proteins
  • Antigen: Human ERK1 recombinant protein
  • Application: WB
  • Specificity: Reacts with human ERK1 and ERK2
  • Target Entrez Gene ID: 5594, 5595

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

ERK1: MAPK3, extracellular signal-regulated kinase 1, insulin-stimulated MAP2 kinase, microtubule-associated protein 2 kinase, PRKM3, ERT2, p44-ERK1, p44-MAPK, HS44KDAP, HUMKER1A, MAP kinase 1, MAPK1. ERK2: MAPK1, extracellular signal-regulated kinase 2, PRKM1, PRKM2, ERT1, p41-ERK1, p41-MAPK, p42-MAPK, MAP kinase 1, MAP kinase 2, MAPK1, MAPK2, p38, p40, p41.




 
 
Products
Cat. # Product Package Size Price # of Units Select
10359A Anti-Human ERK (Clone 5) Mouse IgG MoAb 10 ug $100.00
10359B Anti-Human ERK (Clone 5) Mouse IgG MoAb 100 ug $499.00
 

 



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