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Products >  Cell_Biology >  Cancer_and_Inflammation >  Antibodies_A-G >  CEA_Human_Monoclonal

Anti-Human CEA Mouse IgG MoAb

Carcinoembryonic antigen (CEA) is a glycosylphosphatidylinositol (GPI)-cell surface anchored glycoprotein, first identified in tissue extracts from human colon tumors. The CEA family of genes is part of the immunoglobulin superfamily. In humans, the CEA family consists of 29 genes, 18 of which are normally expressed only during fetal development. Therefore, CEA is not detectable in the blood of healthy adults, but CEA expression is observed in many types of cancer. The measurement of CEA levels has been used in diagnostic tests for colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, lung carcinoma and breast carcinoma, and to detect cancer recurrence after surgical removal of tumors. CEA levels are also elevated in other disease, like ulcerative colitis, pancreatitis, cirrhosis, COPD, and Crohn's disease, as well as in smokers. Immunohistochemical tests using anti-CEA antibodies are used to distinguish different types of carcinomas.

These products are affinity-purified IgG antibodies that recognize human CEA. The antibodies were raised in mouse using human CEA, and can be used for immunohistochemical (IHC) detection of human CEA.

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Features

  • Cat.#: 10094A, 10094B, 10094C
  • Target Name: Human CEA
  • Antigen: Human CEA
  • Clone: 1B2
  • Application: IHC
  • Specificity: Does not cross-react with CEA antisera such as nonspecific cross-reacting antigen (NCA) derived from lung and spleen, NCA-2 derived from embryo stool, normal fecal antigen-1 (NFA-1) derived from normal adult stool, or NFA-2

  • Cat.#: 11021A
  • Target Name: Human CEA
  • Antigen: Human CEA
  • Clone: 1B2
  • Application: IHC
  • Specificity: Does not cross-react with NCA derived from lung and spleen, or NCA-2 derived from embryo stool

  • Cat.#: 11022A
  • Target Name: Human CEA
  • Antigen: Human CEA
  • Clone: 2C3
  • Application: IHC
  • Specificity: Cross-reacts with NCA derived from lung and spleen, NCA-2 derived from embryo stool, NFA-1 derived from normal adult stool, and NFA-2

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Immunohistochemical techniques: 4–10 µg/mL (Cat.# 10094), 100–200X (Cat.# 11021, 11022)

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

Carcinoembryonic antigen-related cell adhesion molecule, CD66, meconium antigen, biliary glycoprotein, BGP




 
 
Products
Offers Cat. # Product Contents Size Price Units Select
  10094C Anti-Human CEA (1B2) Mouse IgG MoAb 500 ug $1,000.00
  10094A Anti-Human CEA (1B2) Mouse IgG MoAb 20 ug $113.00 *
  10094B Anti-Human CEA (1B2) Mouse IgG MoAb 200 ug $499.00
11021A Anti-Human CEA (1B2) Mouse IgG MoAb 1 mL $499.00
  11022A Anti-Human CEA (2C3) Mouse IgG MoAb 1 mL $499.00
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