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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_O-S >  Septin_7_Human

Anti-Human Septin 7 Rabbit IgG Antibody

The septin gene family of nucleotide binding proteins were originally identified in yeast as cell division regulatory proteins. Septin 7 is highly similar to yeast CDC10 protein, and is similar to Drosophila Diff 6 and mouse H5. Each of these proteins contains a GTP-binding motif. Septin 7 is also known as cell division cycle 10 (CDC10) homolog (S. cerevisiae), CDC3, CDC10, SEPT7A, and NBLA02942. It functions in gliomagenesis and in the suppression of glioma cell growth. It is required for the association of centromere-associated protein E with the kinetochore during mitosis. Alternative splicing results in multiple isoforms of septin-7. Abnormal expression patterns of some septins have been reported in human cancers and neurodegenerative diseases.

This product is an affinity-purified IgG antibody that recognizes human septin 7 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human septin 7 protein.

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Features

  • Cat.#: 18991A, 18991B
  • Target Name: Human septin 7 protein
  • Antigen: Human septin 7 C-terminal synthetic peptide
  • Application: WB, IHC, IP
  • Specificity: Cross-reacts with mouse and rat septin 7
  • Target Entrez Gene ID: 989

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.1–1.0 µg/mL
  • Immunohistochemical techniques: 1–5 µg/mL
  • Immunoprecipitation: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Cell division cycle 10 (CDC10) homolog (S. cerevisiae), CDC3, CDC10, SEPT7A, NBLA02942




 
 
Products
Cat. # Product Contents Size Price Units Select
18991A Anti-Human Septin 7 (C) Rabbit IgG Affinity Purify 10 ug $113.00 *
18991B Anti-Human Septin 7 (C) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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