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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_O-S >  Septin_4_Human

Anti-Human Septin 4 Rabbit IgG Antibody

The septin family of nucleotide-binding proteins was originally identified in yeast as cell division regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse; they are thought to regulate cytoskeletal organization. Septin 4 is encoded by the SEPT4 gene in humans and is expressed at high levels in brain and heart. It is a filament-forming GTPase that is localized to the cytoskeleton. Septin 4 may also play a role in cytokinesis. Septin 4 exists as several isoforms, one of which (ARTS) is found in mitochondria and is implicated in apoptosis and cancer. Septin 4 is also known as apoptosis-related protein in the TGF-beta signaling pathway (ARTS), bradeion beta, brain protein H5, H5, MART, SEP4, cell division control-related protein 2, cerebral protein 7, CE5B3, CE5B3 beta, Peanut-like protein 2 (PNUTL2), hucep-7, hCDCREL-2, and septin-M.

These products are affinity-purified IgG antibodies that recognize human septin 4 protein. The antibodies were raised in rabbit using synthetic peptides and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human septin 4 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18987A, 18987B
  • Target Name: Human septin 4 protein
  • Antigen: Human septin 4 N-terminal synthetic peptide
  • Specificity: Cross-reacts with mouse and rat septin 4
  • Application: WB, IHC
  • Target Entrez Gene ID: 5414

  • Cat.#: 18989A, 18989B
  • Target Name: Human septin 4 protein
  • Antigen: Human septin 4 C-terminal synthetic peptide
  • Specificity: Cross-reacts with mouse and rat septin 4
  • Application: WB, IHC
  • Target Entrez Gene ID: 5414

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunohistochemical techniques: 1–5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3.To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

SEPT4, apoptosis-related protein in the TGF-beta signaling pathway, ARTS, bradeion beta, brain protein H5, H5, MART, SEP4, cell division control-related protein 2, cerebral protein 7, CE5B3, CE5B3 beta, Peanut-like protein 2, PNUTL2, hucep-7, hCDCREL-2, septin-M




 
 
Products
Cat. # Product Package Size Price # of Units Select
18987A Anti-Human Septin 4 (N) Rabbit IgG Affinity Purify 10 ug $113.00 *
18987B Anti-Human Septin 4 (N) Rabbit IgG Affinity Purify 100 ug $499.00
18989A Anti-Human Septin 4 (C) Rabbit IgG Affinity Purify 10 ug $113.00 *
18989B Anti-Human Septin 4 (C) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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