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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_O-S >  Olig2_Human

Anti-Human Olig2 Rabbit IgG Antibody

Oligodendrocyte lineage transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. It is also known as protein kinase C binding protein 2 (PRKCBP2), oligodendrocyte transcription factor 2, oligodendrocyte-specific bHLH transcription factor 2, BHLHB1, bHLHe19, OLIGO2, and RACK17. Olig2 protein plays an essential role in regulating the development of oligodendrocytes and motor neurons. Chromosomal translocations in the OLIG2 gene have been associated with T-cell acute lymphoblastic leukemia (T-ALL) and development of Down syndrome. Olig2 expression is useful in distinguishing diffuse gliomas from other types of brain tumors.

This product is an affinity-purified IgG antibody that recognizes human Olig2 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human Olig2 protein.

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Features

  • Cat.#: 18953A, 18953B
  • Target Name: Human Olig2 protein
  • Antigen: Human Olig2 C-terminal synthetic peptide
  • Application: WB, IHC
  • Specificity: Cross-reacts with mouse and rat Olig2
  • Target Entrez Gene ID: 10215

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 2 µg/mL
  • Immunohistochemical techniques: 0.1–1 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Protein kinase C binding protein 2, PRKCBP2, oligodendrocyte transcription factor 2, oligodendrocyte-specific bHLH transcription factor 2, BHLHB1, bHLHe19, OLIGO2, RACK17




 
 
Products
Cat. # Product Contents Size Price Units Select
18953A Anti-Human Olig2 Rabbit IgG Affinity Purify 10 ug $113.00 *
18953B Anti-Human Olig2 Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 

 
 

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