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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_G-N >  GLUT-1_Human

Anti-Human GLUT-1 Rabbit IgG Antibody

Metabolism in mammalian cells requires a constant supply of glucose. Since glucose is a hydrophilic molecule, it must be transported across the cell membrane by dedicated proteins, known as glucose transporters. In humans, these proteins are encoded by the facilitative glucose transporter (GLUT) gene family, now known as the solute carrier family 2 or SLC2A gene family. GLUT1 was the first member of this family to be characterized. It is responsible for the basal glucose uptake needed for respiration in all cells. Expression levels of GLUT1 in cell membranes vary inversely with glucose concentration. GLUT1 can also transport other pentose and hexose sugars. Aerobic glycolysis in tumor cells requires high levels of glucose, and GLUT1 has been targeted in cancer research. GLUT1 is also known as solute carrier family 2 (facilitated glucose transporter), member 1 (SLC2A1); glucose transporter type 1, erythrocyte/brain; HepG2 glucose transporter, GLUT, PED, DYT9, DYT17, DYT18, EIG12, and GLUT1DS.

This product is an affinity-purified IgG antibody that recognizes human GLUT1 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human GLUT1 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18901A, 18901B
  • Target Name: Human GLUT1 protein
  • Antigen: Human GLUT1 C-terminal synthetic peptide
  • Application: WB, IHC
  • Target Entrez Gene ID: 6513

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1 µg/mL
  • Immunohistochemical techniques: 1 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Solute carrier family 2 (facilitated glucose transporter), member 1; glucose transporter type 1, erythrocyte/brain; HepG2 glucose transporter, SLC2A1, GLUT, PED, DYT9, DYT17, DYT18, EIG12, GLUT1DS




 
 
Products
Cat. # Product Package Size Price # of Units Select
18901A Anti-Human GLUT-1 Rabbit IgG Affinity Purify 10 ug $113.00 *
18901B Anti-Human GLUT-1 Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 


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