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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_A-F >  CRMP-2_Human_Monoclonal

Anti-Human CRMP-2 Mouse IgG MoAb

The collapsin response mediator protein (CRMP) family of intracellular phosphoproteins are predominantly expressed in the nervous system during development. These proteins play important roles in axon formation from neurites, and in neuron guidance, growth, and polarity. CRMP-2 is encoded by the DPYSL2 gene in humans. It is also known as dihydropyrimidinase-like 2 (DRP2), dihydropyrimidinase-related protein 2 (DHPRP2), unc-33-like phosphoprotein 2 (ULIP2), and N2A3. CRMP-2 promotes microtubule assembly and is required for growth cone collapse. It also plays a role in synaptic signaling through interactions with calcium channels. Mutations in the DPYSL2 gene have been implicated in multiple neurological disorders. A hyperphosphorylated form of CRMP-2 may play a key role in the development of Alzheimer's disease.

These products are affinity-purified IgG antibodies that recognize human CRMP-2 protein. The antibodies were raised in mouse using recombinant proteins or brain tissue homogenates, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human CRMP-2 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 11096A, 11096B
  • Target Name: Human CRMP-2 protein
  • Antigen: Recombinant human CRMP-2 protein
  • Clone: C4G
  • Application: WB, IP
  • Specificity: Cross-reacts with mouse and rat CRMP-2
  • Target Entrez Gene ID: 1808

  • Cat.#: 11098A, 11098B
  • Target Name: Human CRMP-2 protein
  • Antigen: Recombinant human CRMP-2 protein
  • Clone: N3E
  • Application: WB
  • Specificity: Cross-reacts with mouse and rat CRMP-2
  • Target Entrez Gene ID: 1808

  • Cat.#: 29060A, 29060B
  • Target Name: Human CRMP-2 protein (phosphorylated)
  • Antigen: Brain tissue homogenate
  • Clone: 3F4
  • Application: WB, IHC
  • Specificity: Cross-reacts with mouse and rat CRMP-2
  • Target Entrez Gene ID: 1808

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunohistochemical techniques: n/a
  • Immunoprecipitation: 5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

dihydropyrimidinase-like 2, DRP2, dihydropyrimidinase-related protein 2, DHPRP2, unc-33-like phosphoprotein 2, ULIP2, N2A3




 
 
Products
Cat. # Product Package Size Price # of Units Select
11096A Anti-Human CRMP-2 (C4G) Mouse IgG MoAb 10 ug $113.00 *
11096B Anti-Human CRMP-2 (C4G) Mouse IgG MoAb 100 ug $499.00
11098A Anti-Human CRMP-2 (N3E) Mouse IgG MoAb 10 ug $113.00 *
11098B Anti-Human CRMP-2 (N3E) Mouse IgG MoAb 100 ug $499.00
29060A Anti-Human CRMP-2 (Phosphorylated) (3F4) Mouse IgG MoAb 10 ug $113.00 *
29060B Anti-Human CRMP-2 (Phosphorylated) (3F4) Mouse IgG MoAb 100 ug $535.00
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