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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_A-F >  CDCrel-1_Human

Anti-Human CDCrel-1 (C354) Rabbit IgG Antibody

The septin gene family of nucleotide binding proteins were originally identified in yeast as cell division regulatory proteins. Septin 5--also known as CDCrel-1, HCDCREL-1, peanut-like 1 (Pnutl1), platelet glycoprotein Ib beta chain--is encoded by the SEPT5 gene in humans. A translocation involving the MLL gene and the SEPT5 gene has been reported in acute myeloid leukemia. Alternative splicing results in several septin 5 variants. Septin 5 is known to interact with septin 8 and Parkin 8; mutations in the Parkin 8 gene are implicated in dopaminergic cell death and consequent development of an autosomal recessive form of Parkinson's disease.

This product is an affinity-purified IgG antibody that recognizes human CDCrel-1 protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human CDCrel-1 protein.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18921A, 18921B
  • Target Name: Human CDCrel-1 protein
  • Antigen: Human CDCrel-1 C-terminal synthetic peptide
  • Application: WB, IHC, IP
  • Specificity: Cross-reacts with mouse and rat CDCrel-1
  • Target Entrez Gene ID: 5413

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1 µg/mL
  • Immunohistochemical techniques: 2 µg/mL
  • Immunoprecipitation: 3 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Septin 5, HCDCREL-1, peanut-like 1, Pnutl1, platelet glycoprotein Ib beta chain




 
 
Products
Cat. # Product Package Size Price # of Units Select
18921A Anti-Human CDCrel-1 (C354) Rabbit IgG Affinity Purify 10 ug $113.00 *
18921B Anti-Human CDCrel-1 (C354) Rabbit IgG Affinity Purify 100 ug $499.00
* You must log in if you would like to purchase these products online, since the purchase of these products may be restricted depending on your account type. Researchers at not-for-profit accounts receive a limited use license with their purchase of the product. Researchers at for-profit accounts must obtain a license prior to purchase. For details please contact licensing@clontech.com.
 

 



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