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Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_14-3-3 >  14-3-3_Human

Anti-Human 14-3-3 Protein Rabbit IgG Antibody

The 14-3-3 family of conserved regulatory proteins is expressed in all eukaryotic cells and are encoded by seven genes in mammals. 14-3-3 proteins bind many types of signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 100 signaling proteins have been reported as 14-3-3 ligands. The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE-cellulose chromatography and starch-gel electrophoresis. Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. members of this family play diverse roles, including cell signaling, cell cycle regulation, and regulation of insulin sensitivity.

This product is an affinity-purified IgG antibody that recognizes human 14-3-3 proteins. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human 14-3-3 proteins.

At-A-Glance Documents Images & Data

Features

  • Cat.#: 18649A, 18649B
  • Target Name: Human 14-3-3 proteins
  • Antigen: Human 14-3-3-gamma synthetic peptide
  • Application: WB, IHC
  • Specificity: Reacts with human 14-3-3-beta, -gamma, -epsilon, -zeta, -eta, and -tau proteins
  • Target Entrez Gene ID: 7532

Applications

Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1-5 µg/mL

Storage

Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.

Form

Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation proteins, protein kinase C inhibitor protein 1




 
 
Products
Cat. # Product Package Size Price # of Units Select
18649A Anti-Human 14-3-3 Protein Rabbit IgG Affinity Purify 10 ug $100.00
18649B Anti-Human 14-3-3 Protein Rabbit IgG Affinity Purify 100 ug $499.00
 

 



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