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Cell Biology

Products >  Cell_Biology >  Brain_and_CNS >  Antibodies_14-3-3 >  14-3-3_Eta_Human

Anti-Human 14-3-3-Eta Protein Rabbit IgG Antibody

The 14-3-3 family of conserved regulatory proteins is expressed in all eukaryotic cells and are encoded by seven genes in mammals. 14-3-3 proteins bind many types of signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 100 signaling proteins have been reported as 14-3-3 ligands. The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE-cellulose chromatography and starch-gel electrophoresis. Elevated amounts of 14-3-3 proteins are found in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. The 14-3-3-eta protein shows 99% similarity to the mouse, rat, and bovine orthologs. It is also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, YWHAH, YWHA1, and protein AS1. The YWHAH gene contains a 7-bp repeat in its 5' UTR; changes in the number of this repeat have been associated with early-onset schizophrenia.

This product is an affinity-purified IgG antibody that recognizes human 14-3-3-eta protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human 14-3-3-eta protein.

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  • Cat.#: 18645A, 18645B
  • Target Name: Human 14-3-3-eta protein
  • Antigen: Human 14-3-3-eta N-terminal synthetic peptide
  • Application: WB, IHC
  • Specificity: Does not cross-react with other 14-3-3 proteins
  • Target Entrez Gene ID: 7533


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunohistochemical techniques: 5 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C,


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O.

Alternative names

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, YWHAH, YWHA1, protein AS1

Offers Cat. # Product Contents Size Price Units Select
18645A Anti-Human 14-3-3 eta Protein Rabbit IgG Affinity Purify 10 ug $113.00 *
  18645B Anti-Human 14-3-3 eta Protein Rabbit IgG Affinity Purify 100 ug $499.00
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