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Products >  Cell_Biology >  Bone_Research >  Antibodies >  Procollagen_Type_I_C-Peptide_Human_Monoclonal

Human Anti-Procollagen Type I C Monoclonal Antibody

Human Anti-Procollagen Type I C Monoclonal Antibody (Clone PC5-5 and Clone PC8-7) recognizes procollagen type I C peptide (also known as PIP). These antibodies are suitable for detecting non-denatured antigen in tissue culture media as well as monitoring collagen synthesis in tissue samples. Procollagens are precursor molecules to Collagens (types I, II, III, IV and V) and contain additional peptide sequences ("propeptides") at both their amino- and carboxy-terminal ends. These additional peptide sequences facilitate the winding of procollagen molecules into a triple-helical conformations within the endoplasmic reticulum. The propeptides are then cleaved from the collagen triple helices during secretion, upon which the collagen proteins polymerize into extracellular collagen fibrils.

At-A-Glance Documents Images & Data Resources

Applications

  • Measurement of procollagen type I C peptide (PIP) in cell culture supernatant
  • Immunohistochemical analysis of paraffin-embedded and frozen tissue sections
  • Western blot analysis using non-reducing and non-heating conditions

Source

CloneCat.#ImmunogenImmunized hostSubclassAntibody titer
PC5-5M011human procollagen type I C peptideBALB/c mouseIgG11:10,000
PC8-7M012human procollagen type I C peptideBALB/c mouseIgG11:10,000

Storage

4°C

Stock solution (2.0 mg/ml) should be stored in aliquots at -20°C for 1 year or at 4°C for 6 months.

Notes

For research use only. Not intended for diagnostic or therapeutic use.

Form

Lyophilized

Reconstitution

Dissolve the lyophilized antibody in 50 µl of distilled water (final concentration: 2.0 mg/ml).

References

1. Akiyama, M. & Nakamura, M. (2009) Cell Transplantation 18:443-452.

2. Taubman, M. et al. (1974) Science 186:1115-1117.

Specificity

  • These products specifically react with procollagen type I C peptide.
  • These products cross-react with human, bovine, horse and dog procollagen.
  • These products do not cross-react with rat and rabbit procollagen.



 
 
Products
Cat. # Product Package Size Price # of Units Select
M011 Monoclonal Anti-Human Procollagen Type I C-Peptide (PIP) (Clone PC5-5) 0.1 mg $315.00
M012 Monoclonal Anti-Human Procollagen Type I C-Peptide (PIP) (Clone PC8-7) 0.1 mg $315.00
 

 

Recommended Products
Cat. # Product Package Size Price # of Units Select
MK101 Procollagen Type I C-Peptide (PIP) EIA Kit 96 Assays $540.00
 

 


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