Cre Recombinase Gesicles are cell-derived nanovesicles containing concentrated Cre recombinase protein that give you full control over your recombinase experiments. When applied to your target cells, they fuse with the plasma membrane and discharge active Cre recombinase into the cell, where it carries out Cre-mediated recombination between LoxP sites. Cre Recombinase Gesicles minimize the risk of unintended recombination events because the Cre recombinase coding gene is not present, which eliminates the risk of sustained expression in your cells.
- No Cre coding gene—Eliminate persistent expression; Cre is present only when you want it
- Quick, easy protocol—Just apply 10–20 μl gesicles to your target cells
- Active protein delivery—See faster, more efficient recombination
- Experimental flexibility—Use with dividing and non-dividing cells, primary cells, and cell lines